Understanding how cells communicate both spatially and temporally in an article by Liu et al.

Sendurai Mani shared on LinkedIn:

“Adult human bodies are made up of nearly 36 trillion cells, each interacting constantly with its neighbors.

Every cell has about 20,000 genes, which are expressed based on signals they receive from their environment, including surrounding cells.

When these interactions become abnormal, they can lead to various diseases. Understanding how cells communicate both spatially (in relation to each other) and temporally (over time) is crucial for advancing medical science.

This review article by Liu et al., explores the latest advances in cellular and spatial omics technologies that are helping to unravel these complex interactions.”

Source: Sendurai Mani/LinkedIn

Spatiotemporal omics for biology and medicine.

Authors: Longqi Liu, Ao Chen, Yuxiang Li, Jan Mulder, Holger Heyn, and Xun Xu.

Sendurai A. Mani is a distinguished Indian-American oncologist and molecular biologist. Currently holding the Dean’s Chair for Translational Oncology at Brown University Warren Alpert Medical School, Dr. Mani also serves as the Associate Director for Translational Oncology at the Legorreta Cancer Center at Alpert Medical School.

Dr. Mani’s research focuses on finding the mechanisms driving cancer metastasis and therapy resistance, particularly in breast cancer. He is renowned for his discovery of cancer stem cells and their role in tumor progression and treatment resistance.