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Rami Manochakian: Neoadjuvant osimertinib in stage I-IIIA EGFRm NSCLC did not meet primary endpoint
Jul 21, 2024, 13:36

Rami Manochakian: Neoadjuvant osimertinib in stage I-IIIA EGFRm NSCLC did not meet primary endpoint

Rami Manochakian shared a post on X:

Hot off the press.

Neoadjuvant Osimertinib for the Treatment of Stage I-IIIA Epidermal Growth Factor Receptor–Mutated Non–Small Cell Lung Cancer: A Phase II Multicenter Study.

Authors: Collin M. Blakely, Anatoly Urisman, Matthew A. Gubens, Claire K. Mulvey, Greg M. Allen, Stephen C. Shiboski, Julia K. Rotow, Turja Chakrabarti, D. Lucas Kerr, Jacqueline V. Aredo, Bianca Bacaltos, Megan Gee, Lisa Tan, Kirk D. Jones, W. Patrick Devine, Robert C. Doebele, Dara L. Aisner, Tejas Patil, Erin L. Schenk, Trever G. Bivona, Jonathan W. Riess, Melissa Coleman, Johannes R. Kratz, David M. Jablons.

Just published at Journal of Clinical Oncology. 

Results of phase 2 clinical trial (27 patients) of neoadjuvant osimertinib in stage I-IIIA EGFRm non-small cell lung cancer. Study DID NOT meet primary endpoint.

MPR rate: 14.8%.”

Rami Manochakian

Source: Rami Manochakian/X

Rami Manochakian is a thoracic medical oncologist at Mayo Clinic, Florida. He specializes in thoracic malignancies, including lung cancer, mesothelioma, and thymic tumors, he has dedicated his career to advancing the field of oncology.  He is also recognized as a leader in medical education, serving in various educational  roles at Mayo Clinic and national and international medical societies, including ASCO, ALA, and IASLC.