Cancer Discovery

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September, 2024
September 2024
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Cancer Discovery
Sep 9, 2024, 17:52 | Blog
Michael Rothenberg: A next generation BRAF Inhibitor shows promise in treatment refractory cancer patients
Michael Rothenberg, Chief Medical Officer at Insitro, shared on LinkedIn: "The Pfizer, Pfizer Boulder Research Unit,…
Sep 7, 2024, 10:15 | Insight
Leo Meriranta: KLHL6 targeting the B-cell receptor and lymphoma mutations
Leo Meriranta shared on X: “Friends! I am super-excited to share our story on KLHL6…
Sep 2, 2024, 09:01 | Insight
Mrinal Patnaik: ARNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis
Mrinal Patnaik, Physician Scientist with the Division of Hematology, Department of Internal Medicine at Mayo…
Sep 2, 2024, 07:05 | Insight
Samuel Bakhoum: The role of mitochondria and free radicals in promoting the collapse of cancer micronuclei
Samuel Bakhoum, Associate Member (Professor) in HOPP and Radiation Oncology, Memorial Sloan Kettering Cancer Center,…
Aug 29, 2024, 17:26 | Blog
Natasha Rekhtman: Chromothripsis-mediated Small Cell Lung Cancer
Natasha Rekhtman posted on X: "Hot off the press from team Memorial Sloan Kettering Cancer…
Aug 14, 2024, 18:18 | Insight
Epigenetic and Oncogenic Inhibitors target KRAS-mutant Colorectal Cancers
Elizabeth McKenna shared a post on X about a recent paper by Patrick Loi et…
Aug 10, 2024, 13:39 | Insight
Botensilimab’s effectiveness against tumours poorly responsive to conventional immunotherapy
Justin Stebbing shared a post on LinkedIn:  “Congratulations to Dhan Chand and the Agenus team…
Aug 6, 2024, 11:02 | Blog
Elizabeth McKenna: The August issue of Cancer Discovery is now online
Elizabeth McKenna shared a post on X: "The August issue of Cancer Discovery is now online!…
Jul 31, 2024, 15:50 | Blog
Juan Cubillos-Ruiz: Iron chelation therapy unleashes innate immune responses that control Ovarian Cancer
Juan Cubillos-Ruiz,  Associate Professor for Infection and Immunology at Well Corner Medicine, shared on X:…
Jul 31, 2024, 10:17 | Opinion
Tito Sandoval: Cubillos-Ruiz Lab's latest study about iron chelation therapy for ovarian cancer
Tito Sandoval, Senior Scientist at Washington University School of Medicine in St. Louis, shared on X…
Jul 28, 2024, 12:52 | Insight
Jaehyuk Choi: A tour-de-force cellular and transcriptional dissection of Merkel cell carcinoma
Jaehyuk Choi, Associate Professor at Northwestern University, shared a post on X about a recent…
Jul 28, 2024, 12:47 | Insight
MARK2/MARK3 Kinases Are Catalytic Co-dependencies of YAP/TAZ in Human Cancer
Elizabeth McKenna, Executive Editor of Cancer Discovery, shared a post on X about a recent…
Jul 23, 2024, 10:34 | Insight
The EACR's highlights in cancer research
The European Association for Cancer Research (EACR) shared on X: “The EACR's Highlights in Cancer…
Jul 20, 2024, 10:27 | Blog
Elizabeth McKenna: The SCRUM-MONSTAR Cancer-Omics Ecosystem
Elizabeth McKenna shared a post on X: ''Now online in Cancer Discovery: The SCRUM-MONSTAR Cancer-Omics…
Jul 19, 2024, 22:19 | Insight
Yüksel Ürün: Congratulations all new participants of the ASCO Leadership Development Program!
Yüksel Ürün shared a post by Miriam Knoll, on X, adding: "Congratulations to you and…
Jul 16, 2024, 03:13 | Blog
Haniel Araujo: Efficacy of the novel RAS(ON) in KRASG12C mutant NSCLC
Haniel Araujo, Thoracic and Head and Neck Medical Oncology Fellow at MD Anderson Cancer Center, shared…
Jul 14, 2024, 15:02 | Insight
Bruno Giotti: Multiple gene programs and cellular subpopulations associated with patient prognosis in pleural mesothelioma
Bruno Giotti, Postdoctoral Researcher at Icahn School of Medicine at Mount Sinai, shared a post…
Jul 14, 2024, 04:21 | Insight
Elizabeth McKenna: 4 papers with variations on the theme of cancer cell plasticity as a mechanism of resistance to KRAS inhibition
Norbert Kraut, Global Head of Cancer Research Boehringer Ingelheim, shared a post by Elizabeth McKenna,…
Jul 11, 2024, 14:56 | Insight
Simona Cristea: The multi-facet process of resistance to KRAS inhibitors in pancreatic cancer
Simona Cristea, Head of Data Science at Hale Center for Pancreatic Cancer, shared a post by…
Jul 7, 2024, 16:08 | Insight
Tumor Microenvironment Gradients in Pleural Mesothelioma
Elizabeth McKenna shared on X: "Now online in Cancer Discovery: Single-cell View of Tumor Microenvironment Gradients…
Jul 5, 2024, 16:30 | Insight
CAR NK cells with CD28 costimulation improved cell persistence and antitumor activity
Adding CD28 costimulation to cord blood-derived chimeric antigen receptor (CAR) natural killer (NK) cells targeting…
Jul 5, 2024, 14:17 | Blog
Whijae Roh: The history of chromosomal instability in genome doubled tumors
Whijae Roh, Senior Computational Biologist at Pfizer, shared a post by Elizabeth McKenna, on X: "The history…
Jul 5, 2024, 13:43 | Insight
Stromal Interleukin-33 Directs the Pancreatic Microenvironment to Promote Tumor Growth
‘Oncogenic KRAS-dependent stromal interleukin-33 directs the pancreatic microenvironment to promote tumor growth.’ This paper was…
Jul 4, 2024, 14:44 | Insight
Elizabeth McKenna: The July issue of Cancer Discovery is now online
Elizabeth McKenna shared a post on LinkedIn: “The July issue of Cancer Discovery is now online!…
Jul 4, 2024, 11:09 | Insight
Impact of Antibiotic Preconditioning on Microbiome and Immunity
Anirban Maitra shared on X: "The July issue of Cancer Discovery is online! Featuring a…
Jun 30, 2024, 13:42 | Blog
Sumanta K. Pal discusses CD70-Targeted Allogeneic CAR T-Cell Therapy for ccRCC - Cancer Discovery
Cancer Discovery shared on X: "Published by a nonprofit professional society, the journal enhances knowledge…
Jun 30, 2024, 05:23 | Blog
María Mayán: How and why becoming an editor
María Mayán, Research Group Leader at CINBIO, shared on X/Twitter: . "Lunch session with editors:…
Jun 28, 2024, 06:45 | Positive
Patrick Hwu: Moffitt Cancer Center is at the forefront of cancer discovery
Patrick Hwu shared on X: "Bioengineering is vital to making strides in cancer discovery, and…
Jun 25, 2024, 12:52 | Blog
Tali Lev: Excited to attend the ⁦Metastasis Research Society 20th Biennial meeting
Tali Lev, Senior Editor at Cancer Discovery, made the following post on X: . "Hi from…
Jun 25, 2024, 12:48 | Blog
Engaging with the community at the forefront of cancer science and medicine - Cancer Discovery
Cancer Discovery shared on X:  . “Engaging with the community at the forefront of cancer…
Jun 23, 2024, 13:22 | Insight
Katy Rezvani: Exciting research on CD70-targeting CAR NK cells
Katy Rezvani shared Elizabeth McKenna's post on X, adding: "Many congratulations to our Dr. Sunil…
Jun 18, 2024, 14:39 | Insight
Personalised support from experienced in-house editors - AACR Journals
Elizabeth McKenna shared a post by AACR Journals on LinkedIn, adding: “Reach out to the Cancer…
Jun 9, 2024, 06:40 | Insight
W. Gregory Sawyer: Engineering Cancers End
W. Gregory Sawyer, Moffitt Cancer Center Chief BioEngineering Officer, shared on X: “Engineering Cancers End.…
May 30, 2024, 06:33 | Career
Bailee Sliker: I start a new chapter as an Oncology Scientist/Medical Writer at NCCN
Bailee Sliker, Oncology Scientist/Medical Writer at the National Comprehensive Cancer Network (NCCN), shared on X:…
May 4, 2024, 16:54 | Insight
Elizabeth McKenna: The May issue of Cancer Discovery
Elizabeth McKenna shared on LinkedIn: "The May issue of Cancer Discovery is now online! The…
May 4, 2024, 10:27 | Insight
Paolo Tarantino: HER2 is about to change again
Paolo Tarantino shared a previous post of him on X and added: "HER2 is about…
May 2, 2024, 23:03 | Career
Steven Kridel: I’m starting a new position as Chair of Department of Cancer Biology at Wake Forest University School of Medicine!
Steven Kridel, Chair, Department of Cancer Biology at Wake Forest University School of Medicine, made…
May 1, 2024, 11:57 | Blog
Direna Alonso-Curbelo receives Cancer Discovery Early Career Award
Cancer Discovery shared on X/Twitter: "Congratulations, Direna Alonso-Curbelo, on the inaugural Cancer Discovery Early Career Award!…
Apr 20, 2024, 06:57 | Insight
Read an In Focus article by Kimryn Rathmell from the latest issue - Cancer Discovery
Cancer Discovery shared a post on X: “Read an In Focus article by Kimryn Rathmell…
Apr 17, 2024, 00:52 | Insight
UHN Research - Can a blood sample be used to predict patient outcomes to cancer immunotherapy drug pembrolizumab?
UHN Research shared on their LinkedIn: "Can a blood sample be used to predict patient…
Apr 14, 2024, 14:08 | Blog
Danielle Carnival: About Biden Cancer Moonshot progress and global commitment in Cancer Discovery
Danielle Carnival, Deputy Assistant to President Biden for the Cancer Moonshot, shared on X/Twitter: "At the…
Apr 14, 2024, 06:54 | Opinion
Kimryn Rathmell: The National Cancer Plan is meant to drive innovation in cancer research
Kimryn Rathmell, Director of the National Cancer Institute, shared on X/Twitter: "The National Cancer Plan…
Apr 11, 2024, 17:38 | Insight
Vivek Subbiah: Thrilled to be featured in AACR’s special issue of Cancer Discovery
Vivek Subbiah shared a post on X: “Thrilled to be featured in American Association for…
Apr 11, 2024, 15:23 | Drugs
Piotr Wysocki: Adagrasib and cetuximab in KRAS G12C-mutated colorectal cancer is a safe and active
Piotr Wysocki, Professor of Medicine and Head of the Department of Oncology at Jagiellonian University…
Apr 11, 2024, 12:10 | Blog
CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma, by Sumanta K. Pal et al - Cancer Discovery
Cancer Discovery shared on X/Twitter: "Just published with the AACR24 Clinical Plenary presentation: CD70-Targeted Allogeneic CAR…
Apr 11, 2024, 06:46 | Opinion
Maria Natalia Gandur Quiroga: The Hallmarks of Precancer
Maria Natalia Gandur Quiroga shared a post on X: "The Hallmarks of Precancer. AACR Journals,…
Apr 10, 2024, 09:09 | Blog
Vivek Subbiah: Super delighted to meet the amazing Elizabeth McKenna, Executive Editor of Cancer Discovery
Vivek Subbiah shared on X/Twitter: "Super delighted to meet the amazing Elizabeth McKenna, Executive Editor…
Apr 8, 2024, 22:24 | Insight
NSCLC's Immune Landscape: A Comprehensive Study of the Tumor Microenvironment
A recent study, “Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical…
Apr 8, 2024, 15:43 | Blog
Luis Diaz: The most recent issue of Cancer Discovery features our prescient commentaries about the future of cancer research
Luis Diaz, Head of Division of Solid Tumor Oncology at Memorial Sloan Kettering Cancer Center,…
Apr 7, 2024, 23:28 | Insight
Biagio Ricciuti: MET kinase domain mutations as novel & targetable alterations in NSCLC and other cancer types
Biagio Ricciuti, Medical Oncologist at Dana-Farber Cancer Institute, shared on X: "Our collaborative effort to…
Apr 6, 2024, 14:56 | Insight
Kimryn Rathmell: My Cancer Discovery commentary for a new perspective on the National Cancer Plan
Kimryn Rathmell, Director of the National Cancer Institute, recently shared on X: "Ready for AACR24?…
Apr 6, 2024, 12:55 | Societies
Productive Peer Review: Improving Science while Avoiding Pitfalls session at AACR24
The American Association for Cancer Research (AACR) shared a post on X/Twitter: "Productive Peer Review:…
Apr 6, 2024, 08:34 | Opinion
Kimryn Rathmell: My Cancer Discovery commentary for a new perspective on the National Cancer Plan
Kimryn Rathmell, Director of NCI, shared on X/Twitter: "Ready for AACR24? Before we hit the…
Mar 20, 2024, 23:02 | Blog
Attending the NIH-CZI Junior Investigators Atlas Builders Meeting? - Cancer Discovery
Cancer Discovery made the following post on X: "Are you attending the NIH-CZI Junior Investigators…
Mar 8, 2024, 19:03 | Insight
Lea Monteran: TIGIT blockade with MDSC inhibition may be a novel and promising therapeutic strategy to treat bone metastasis
Lea Monteran, Ph.D. student at Tel Aviv University, shared on X/Twitter: "I am excited to…
Feb 27, 2024, 19:29 | Blog
Eric Stutheit-Zhao: A blood sample can track immunotherapy response
Eric Stutheit-Zhao, Resident Doctor at Department of Radiation Oncology, University of Toronto, shared a post…
Feb 24, 2024, 16:50 | Blog
Toni Choueiri: New insights from the JAVELIN Renal 101 trial in RCC in Cancer Discovery
Toni Choueiri, Professor of Medicine at Harvard Medical School and Director of the Lank Center for…
Feb 1, 2024, 13:52 | Blog
Yuki Saito: A pan-cancer landscape of driver alterations and their clinical actionability in Japanese patients
Yuki Saito, Postdoctoral researcher at Keisuke Kataoka Laboratory, shared a post by Keisuke Kataoka Laboratory…
Jan 18, 2024, 16:08 | Insight
Yüksel Ürün: Exciting news for cancer patients and researchers alike!
Yüksel Ürün, Professor at the Department of Medical Oncology at the Ankara University School of…
Dec 24, 2023, 18:34 | Insight
Norbert Kraut: A must-read Precision Oncology: 2023 in Review
Norbert Kraut, Global Head of Cancer Research, Boehringer Ingelheim, shared on X/Twitter: "2023 has been…
Dec 16, 2023, 11:12 | Insight
Ron DePinho: December issue of Cancer Discovery is now online
 Ron DePinho, Professor and Past President MD Anderson Cancer Center, shared on X: "December issue…
Dec 6, 2023, 15:38 | Insight
Vivek Subbiah: Terrific review out in Cancer Discovery
Vivek Subbiah shared on LinkedIn: "Terrific review out in Cancer Discovery. Tumor evolution is fueled…
Dec 6, 2023, 11:48 | Opinion
Ruben Mesa: An inspiring read by our Advocate Health CEO Eugene A. Woods
Ruben Mesa, President at Atrium Health Levine Cancer, shared on LinkedIn: "Just finished this inspiring…
Dec 5, 2023, 19:35 | Blog
Vivek Subbiah: Cancer Evolution: A Multifaceted Affair! An amazing review
Vivek Subbiah made the following post on Twitter: "Cancer Evolution: A Multifaceted Affair! An amazing…
Oct 14, 2023, 16:21 | Positive
100 Influential Women in Oncology: Key Opinion Leaders to follow on Social Media in 2023: Part 8
Once again, it's Saturday, and we continue OncoDaily’s series, '100 Influential Women in Oncology: Key…
Sep 28, 2023, 19:04 | Blog
Elizabeth McKenna: Cancer Discovery is issuing a call for short commentaries that challenge existing paradigms or shed new light on arising issues or emerging topics in the field.
Sep 5, 2023, 17:18 | Insight
Vivek Subbiah: Give the right drug, to the right patient, at the right time in every country, to think globally and act locally.
Quoting Vivek Subbiah, Chief of Early-Phase Drug Development at the Sarah Cannon Research Institute, on LinkedIn:…
Sep 2, 2023, 19:03 | Insight
Sumanta K. Pal: We are soon to begin a trial of camu camu with IO in kidney cancer, inspired by Bertrand Routy’s excellent paper in Cancer Discovery, at City of Hope.
Quoting Sumanta K. Pal, the co-director of City of Hope's Kidney Cancer Program, on X/Twitter:…
Aug 11, 2023, 19:30 | Drugs
Vivek Subbiah: Pralsetinib has received FULL FDA approval
Exciting News for RET+ patients! Pralsetinib has received FULL FDA approval! From treating the 1st…
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