Sara Coca Membribes, Clinical Research Fellow to Prof Powles at Barts Health NHS Trust, shared a post on X:
“Final 9-year follow-up of CheckMate214:
- Sustained OS with NIVO+IPI.
- Favorable-risk OS trend favors NIVO+IPI (HR 0.80) with higher CRs and more durable responses.
- RCC-specific survival (HR 0.68) closely paralleled OS (HR 0.69).”
Title: Nivolumab plus ipilimumab versus sunitinib for first-line treatment of advanced renal cell carcinoma: final analysis of efficacy and safety from the phase III CheckMate 214 trial
Authors: T.K. Choueiri, L. Albigès, D.F. McDermott, H.J. Hammers, B. Escudier, M. Burotto, E.R. Plimack, C. Porta, S. George, T. Powles, F. Donskov, M.B. Atkins, H. Gurney, C.K. Kollmannsberger, M.-O. Grimm, C. Barrios, D. Castellano, V. Grünwald, Y. Tomita, B.I. Rini, R. Jiang, M. van Kooten Losio, C.-W. Lee, N.M. Tannir, R.J. Motzer

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