
Praveen Kumar Marimuthu/X
Apr 29, 2025, 09:47
Praveen Kumar Marimuthu: Neoadjuvant dostarlimab for Stage I–III dMMR solid tumors
Praveen Kumar Marimuthu, DM Resident in Medical Oncology at Christian Medical College and Hospital, shared an article by Andrea Cercek, et al. on X:
“Nonoperative Rx of d-MMR tumors NEJM:
Neoadjuvant dostarlimab (500 mg q3w x 6 mo) for Stage I–III dMMR solid tumors (rectal and non-rectal):
- 4/5 had cCR.
- 4/5 avoided surgery.
- 2-yr RFS 92%.
- No Rx-related deaths.
For prostate, GE.”
Nonoperative Management of Mismatch Repair–Deficient Tumors.
Journal: The New England Journal of Medicine
Authors: Andrea Cercek, et al.
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