Pavlina Lenga, Neurosurgeon at the University Hospital Heidelberg, shared a post on LinkedIn about a paper she co-authored with colleagues published in Neurosurgical Review:
“Happy to share our new publication in Neurosurgical Review from the Department of Neurosurgery Heidelberg in collaboration with Neuropathology Heidelberg (Felix Sahm).
In a cohort of 32 adults with pilocytic astrocytoma, infratentorial tumors were associated with higher surgical risks and lower rates of gross-total resection, while recurrence (~50%) correlated with higher Ki-67 rather than extent of resection.
Biological differences to pediatric cases included BRAF alterations only in a subset and the occurrence of HGAP accounting for disease-specific mortality.”
Title: Adult pilocytic astrocytomas: challenging the benign paradigm with surgical risks, recurrence dynamics, and molecular insights
Authors: Dorothea Mitschang, Helena Kleineidam, Felix Hinz, Felix Sahm, Andreas Unterberg, Sandro Krieg, Philip Dao Trong, Pavlina Lenga
You can read the Full Article in Neurosurgical Review.
Read an article on “Astrocytoma: Causes, Symptoms, Diagnosis, Treatment, and 2025 Advances” on OncoDaily.
