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Paolo Tarantino: Long term outcomes from KATHERINE are out
Jan 17, 2025, 09:03

Paolo Tarantino: Long term outcomes from KATHERINE are out

Paolo Tarantino, Clinical Research Fellow at the Dana-Farber Cancer Institute, shared a recent article by Charles E. Geyer et al. on X:

“Long-term outcomes from KATHERINE out in The New England Journal of Medicine.

Post-neoadjuvant escalation of therapy with a HER2 ADC (T-DM1) in patients with HER-positive breast cancer and residual disease meaningfully improves 7-year iDFS (Δ 13.7%) and OS (Δ 4.7%).

Congrats to the authors.”

Survival with Trastuzumab Emtansine in Residual HER2-Positive Breast Cancer

Authors: Charles E. Geyer, Michael Untch, Chiun-Sheng Huang, Max S. Mano, Eleftherios P. Mamounas, Norman Wolmark, Priya Rastogi, Andreas Schneeweiss, Andres Redondo, Hans H. Fischer, Véronique D’Hondt, Alison K. Conlin, Valentina Guarneri, Irene L. Wapnir, Christian Jackisch, Claudia Arce-Salinas, Peter A. Fasching, Michael P. DiGiovanna, John P. Crown, Pia Wuelfing, Zhimin Shao, Elena Rota Caremoli, Hervé R. Bonnefoi, Bryan T. Hennessy, Ljiljana Stamatovic, Hugo Castro-Salguero, Adam M. Brufsky, Adam Knott, Asna Siddiqui, Chiara Lambertini, Thomas Boulet, Beatrice Nyawira, Eleonora Restuccia and Sibylle Loibl

Paolo Tarantino Paolo Tarantino

Dr. Paolo Tarantino, MD, is pursuing an advanced research fellowship at Dana-Farber Cancer Institute and Harvard Medical School, concurrently working towards a PhD in clinical research at the University of Milan.

His research focuses on exploring the HER2 oncoprotein, investigating the emerging HER2-low subgroup of breast tumors, and developing novel antibody-drug conjugates targeting every subtype of breast cancer.

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