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Paolo Tarantino: T-DXd-Related ILD Remains a Major Clinical Challenge
Paolo Tarantino/ LinkedIn

Paolo Tarantino: T-DXd-Related ILD Remains a Major Clinical Challenge

Paolo Tarantino, Vivian Saykaly Visiting Professor in Medical Oncology at McGill University Health Centre, Clinical Research Fellow at Dana-Farber Cancer Institute, Research Fellow at Harvard Medical School, shared on X:

“New, large analysis of T-DXd-related ILD from 🇯🇵.

Among 2801 patients, 381 (14%) developed ILD with T-DXd, of which 30 (7.9%) fatal.

Most cases (83%) recovered, and steroids helped – but neither high-dose steroids nor immunosuppressants helped in G3-4 ILD.”

Title: Real-world characteristics of trastuzumab deruxtecan-related interstitial lung disease in Japanese patients with breast cancer and gastric cancer

Authors: Yutaka Fujiwara, Katsunori Oikado, Tomohisa Baba, Masahiko Kusumoto, Shinichi Sasaki, Masahiro Endo, Terufumi Kato, Yasuyuki Kurihara, Yoshinobu Saito, Kunihiro Yagihashi, Masafumi Sata, Yoshinao Sato, Hirotsugu Kenmotsu, Taiki Fukuda, Teppei Yamaguchi, Saiko Isshiki, Hiroshi Wakui, Haruki Kobayashi, Satoshi Ikeda, Motoyasu Kato, Ou Yamaguchi, Toshimi Takano, Ken Kato, Yoshiharu Hiruma, Koji Hirata, Wataru Hashimoto, Kazuyoshi Kuwano

Read the full article.

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Paolo Tarantino: T-DXd-Related ILD Remains a Major Clinical Challenge

Breast Cancer cancer gastric cancer Haruki Kobayashi Hiroshi Wakui Hirotsugu Kenmotsu ILD Katsunori Oikado Kazuyoshi Kuwano Ken Kato Koji Hirata Kunihiro Yagihashi Lung cancer Masafumi Sata Masahiko Kusumoto Masahiro Endo Motoyasu Kato OncoDaily Oncology Ou Yamaguchi Paolo Tarantino Saiko Isshiki Satoshi Ikeda Shinichi Sasaki T-DXd-related ILD Taiki Fukuda Teppei Yamaguchi Terufumi Kato Tomohisa Baba Toshimi Takano Wataru Hashimoto Yasuyuki Kurihara Yoshiharu Hiruma Yoshinao Sato Yoshinobu Saito Yutaka Fujiwara