May, 2025
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Diego A. Díaz García: First RCT in NSCLC with uncommon EGFR mutations – Afatinib VS Chemotherapy
May 14, 2025, 13:10

Diego A. Díaz García: First RCT in NSCLC with uncommon EGFR mutations – Afatinib VS Chemotherapy

Diego A. Díaz García, Medical Oncologist, CEO and Founder at CánCare, shared a post on X about recent paper Satoru Miura and colleagues authored:

“First RCT in NSCLC with uncommon EGFR mutations: afatinib doubled PFS vs chemo (10.6 vs 5.7 mo).
ACHILLES/TORG1834 Should it be the new 1st-line standard?
Or could 3rd-gen TKIs novel combos do better?”
NSCLC

Title: Pragmatic Randomized Study of Afatinib Versus Chemotherapy for Patients With Non–Small Cell Lung Cancer With Uncommon Epidermal Growth Factor Receptor Mutations: ACHILLES/TORG1834

Journal: Journal of Clinical Oncology

Authors: Satoru Miura, Hiroshi Tanaka, Toshihiro Misumi, Hiroshige Yoshioka, Takaaki Tokito, Tatsuro Fukuhara, Yuki Sato, Yoshimasa Shiraishi, Katsuhiko Naoki, Hiroaki Akamatsu, Ou Yamaguchi, Toshihide Yokoyama, Shoichi Kuyama, Kazumi Nishino, Naoki Furuya, Takayasu Kurata, Terufumi Kato, Satoshi Ikeda, Hidehito Horinouchi, Eiki Ichihara, Masahide Mori, Yuichi Takiguchi, Kentaro Tanaka, Yasuhiro Goto, Hiroaki Okamoto

Read Full Article on ascopubs.org

Non-Small Cell Lung Cancer: Causes, Symptoms, Diagnosis, Treatment Options, and Latest 2025 Advances in Targeted and Immunotherapy

NSCLC Lung cancer