Science
Myeloma Paper of the Day, September 9th, Suggested by Robert Orlowski

Myeloma Paper of the Day, September 9th, Suggested by Robert Orlowski

Robert Orlowski, Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared on X:

“Myeloma Paper of the Day:

Disease control following PD-1 blockade in high-risk smoldering myeloma assoc w/ macrophage reprogramming (CD86 upregulation in DR pairs + IFN-γ-induced HLA-DRA) for antigen spreading rather than CD8⁺ T cell engagement.”

Title: Macrophage reprogramming, not CD8 T cell dynamics, characterizes durable disease control following PD-1 blockade in smoldering myeloma

Authors: Noé Perron, Kane Foster, Tarek H. Mouhieddine, Robert A. Redd, Sophie Magidson, Jacqueline Perry, Ashlee Sturtevant, Christine Davie, Caroline Ricciardi, Frances Arters, Marjorie Marto, Amy Goguen, Yuxin Liu, Elizabeth K. O’Donnell, Adam S. Sperling, Jacob P. Laubach, Paul G. Richardson, Gad Getz, Romanos Sklavenitis-Pistofidis, Lorenzo Trippa, Yoshinobu Konishi, Omar Nadeem, Irene M. Ghobrial

You can read the full article on Leukemia.

Myeloma Paper of the Day, September 9th, Suggested by Robert Orlowski

You can find other articles featuring Robert Orlowski on OncoDaily.

Adam S. Sperling Amy Goguen Ashlee Sturtevant Caroline Ricciardi Christine Davie Elizabeth K. O'Donnell Frances Arters Gad Getz Irene M. Ghobrial Jacob P. Laubach Jacqueline Perry Kane Foster Leukemia Lorenzo Trippa Marjorie Marto Myeloma Paper of the Day Noé Perron Omar Nadeem Paul G. Richardson Robert A Redd Robert Orlowski Romanos Sklavenitis-Pistofidis Sophie Magidson Tarek H. Mouhieddine Yoshinobu Konishi Yuxin Liu