Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research, and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:
“Myeloma Paper of the Day:
High CTC levels associated with high-risk features (ISS or IMS/IMWG 2024), complex genomics (chromothripsis, APOBEC mutagenesis, and loss of key tumor suppressors), and are a surrogate for PR transcriptomic signatures.”
Title: Elevated circulating tumor cells reflect high proliferation and genomic complexity in multiple myeloma
Authors: Juan-Jose Garces, Benjamin Diamond, Tereza Sevcikova, Serafim Nenarokov, Daniel Bilek, Eva Radova, Ondrej Venglar, Veronika Kapustova, Ross Firestone, Kylee Maclachlan, Anish Simhal, Lucie Broskevicova, Jan Vrana, Ludmila Muronova, Tereza Popkova, Jana Mihalyova, Hana Plonkova, Michael Durante, Bachisio Ziccheddu, Michal Simicek, Hearn Jay Cho, George Mulligan, Jonathan Keats, David Zihala, Ola Landgren, Roman Hajek, Saad Usmani, Francesco Maura, Tomas Jelinek
You can read the Full Article in Hemasphere.
You can find more posts featuring Robert Orlowski on OncoDaily.