Melvin LK Chua: Chromatin-related adaptation for acquired Radioresistance in Head and Neck Cancer
Melvin LK Chua, Clinician-Scientist at the NCCS and Duke-NUS Medical School, shared an article by him and colleagues on X:
“Our 2nd work supporting chromatin-related adaptation for acquired Radioresistance in Head and Neck Cancer.
Collaboration with Edward Kai-Hua Chow and talented PhD student Sharon Pei Yi Chan using QPOP that serendipitously showed Panobinostat efficacy against RR HNC Mechanistic work identified HDAC6 as the target.”
Authors: Sharon Pei Yi Chan, Celestia Pei Xuan Yeo, Boon Hao Hong, Evelyn Mui Cheng Tan, Chaw Yee Beh, Eugenia Li Ling Yeo, Dennis Jun Jie Poon, Pek Lim Chu, Khee Chee Soo, Melvin Lee Kiang Chua and Edward Kai-Hua Chow
Dr. Melvin L.K. Chua is a Clinician-Scientist at the NCCS and Duke-NUS Medical School, and Principal Investigator of the Precision Radiotherapeutics and Oncology Programme, Division of Medical Sciences, supported by the NMRC Clinician-Scientist Award. He is also the Head of the Department and Senior Consultant for Head and Neck and Thoracic Cancers, Division of Radiation Oncology, and Director of the Data and Computational Science Core at the NCCS. His research is focused on phase 2-3 trials in nasopharynx (NPC) and prostate cancers (PCa).
He is also on the scientific advisory board for the NPC Guangzhou-Singapore Trial Network, a board member of the Head Neck Cancer International Group (HNCIG), and the Clinical Trials Scientific Committee Chair of HNCIG. Dr. Chuaam’s other academic activities include his present role as the Editor-in-Chief, of Annals of Nasopharynx Cancer and his previous role as the Associate Senior Editor for the Head and Neck Cancer Section of the International Journal of Radiation Oncology Biology Physics – The official journal of the American Society of Radiation Oncology.
More posts featuring Melvin LK Chua.
-
ESMO 2024 Congress
September 13-17, 2024
-
ASCO Annual Meeting
May 30 - June 4, 2024
-
Yvonne Award 2024
May 31, 2024
-
OncoThon 2024, Online
Feb. 15, 2024
-
Global Summit on War & Cancer 2023, Online
Dec. 14-16, 2023