Jennifer Rosenbluth, Associate Professor at University of California, San Francisco, Principal Investigator at Rosenbluth Lab, shared on LinkedIn:
“Our paper is now online at Cell Reports Medicine, evaluating whether I-SPY2 biomarkers predict treatment response in patient-derived breast cancer organoids.
Great work by first author and outstanding graduate student Tam Binh Bui, together with many collaborators, including Laura van ‘t Veer, Denise Wolf and the I-SPY2 team, Laura Esserman, colleagues across the UCSF Breast Care Center, Isaac Harris, and the Dana-Farber IBC Program.
UCSF News also recently published a forward-looking piece on the potential of organoids to improve cancer treatment, based in part on Tam Binh’s work: Could These Tiny Organs Save Millions of Lives?”
Title: Biomarker-guided responses in patient-derived organoids predict effective therapies in breast cancer
Authors: Tam Binh V. Bui, Denise M. Wolf, Michael C. Bruck, Kaitlin Moore, Jessica Lien, Sarah D.W. Choi, Shruti Warhadpande, Amirabbas Parizadeh, Deborah Dillon, Beth Overmoyer, Filipa Lynce, Lamorna Brown-Swigart, Gillian L. Hirst, Christina Yau, Isaac J. Nijman, Boudewijn M.T. Burgering, Isaac S. Harris, Laura J. Esserman, Laura J. van ‘t Veer, Jennifer M. Rosenbluth
Other articles about breast cancer on OncoDaily.