Hannah Abrams, PGY6 at Fred Hutch Cancer Center, shared a post on X:
“Is vaginal estrogen safe in breast cancer?
Nice SEER-Medicare study showing 2 things:
- Likely, yes
- All studies of drug-cancer outcome need to be adjusted for immortal time bias.
Initial analysis: Better survival.
Adjustment for immortal time: no difference.”
Title: Survival Outcomes in Breast Cancer Patients With Use of Vaginal Estrogen Therapy: A SEER Analysis
Authors: Olivia R. Mitchel, Chiu-Hsieh (Paul) Hsu, Leah S. Millheiser, Irene L. Wapnir, Shreya Chandak, Missy Tran, Jennifer Erdrich
Read the article.
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