Fabio Carbone: New Evidence on Single vs Double-Stapled Colorectal Anastomosis
Fabio Carbone/LinkedIn

Fabio Carbone: New Evidence on Single vs Double-Stapled Colorectal Anastomosis

Fabio Carbone, Colorectal Surgeon at IRCCS National Cancer Institute G. Pascale Foundation, Naples, Italy, shared on LinkedIn:

Just published in Surgery! 

Pleased to share our new systematic review and meta-analysis comparing single-stapled (SSA) versus double-stapled (DSA) colorectal anastomosis after anterior resection.

13 comparative studies | 2,537 patients

  • Anastomotic leak: RR 0.77 (95% CI 0.46-1.31)
  • Major complications: RR 0.67 (95% CI 0.37-1.20)
  • No relevant difference in major LARS

Fabio Carbone: New Evidence on Single vs Double-Stapled Colorectal Anastomosis

Overall, SSA appears to be a safe and technically appealing alternative to conventional DSA, although current evidence does not demonstrate superiority of either technique.

Further high-quality, multicentre randomised trials are needed to define whether avoiding crossing staple lines translates into meaningful clinical benefit.”

Title: Single-stapled versus double-stapled colorectal anastomosis after anterior resection: Systematic review and meta-analysis of short-term and functional outcomes

Authors: Antonio Luberto, Fabio Carbone, Daniela Rega, Massimiliano Di Marzo, Caterina Foppa, Antonino Spinelli, Paolo Delrio

Read The Full Article

You may also be interested in: Phase 2 NEST Trial: Neoadjuvant BOT/BAL in Localized Colon Cancer

Fabio Carbone: New Evidence on Single vs Double-Stapled Colorectal Anastomosis