Clara Bodelon, Senior Principal Scientist at American Cancer Society, shared on LinkedIn:
“Proud to see this work led by outstanding American Cancer Society Research postdoctoral fellow, Brigitte Pfluger, published in JAMA Network Open.
In this study of 14,309 cancer survivors, our team examined how genetic predisposition to higher body mass index (BMI) and obesity are associated with the risk of obesity-related second primary cancers.
Brigitte and colleagues found that genetic predisposition to higher BMI was associated with a modest increase in risk, but obesity itself had a substantially stronger association with risk across all levels of genetic susceptibility.
As the population of cancer survivors continues to grow, understanding modifiable risk factors for second primary cancers is increasingly important. These findings highlight the importance of healthy weight management among cancer survivors, regardless of genetic predisposition.
Congratulations to Brigitte and the entire team on this achievement and on advancing the evidence base for cancer survivorship care.”
Title: Body Mass Index, Genetic Predisposition, and Obesity-Related Second Cancer Risk in Cancer Survivors
Authors: Brigitte A. Pfluger, Fetsum Tekalegn, Ellen L. Mitchell, Adriana Lori, Emily L. Deubler, Lauren R. Teras, Alpa V. Patel, Lauren E. McCullough, Clara Bodelon.
You can also read: Clara Bodelon: Genetic BMI Risk and Mortality in Breast Cancer Survivors