Adam Weiner, Urologic Oncologist at Cedars Sinai Medical Center, shared on X:
“Major shift: ACS now directly recommends routine PSA screening for prostate cancer, moving off pure shared decision-making.
- Average risk: PSA every 2 yrs, ages 50-69
- High risk (Black men; first-degree relative dx <65 or multiple at any age): annual PSA, ages 45-69
- Non-Black with one first-degree relative dx ≥65: every 2 yrs, ages 45-69
Age-adjusted elevated = PSA ≥3.0 (ages 45-69) or ≥6.5 (70-74); repeat in 2 wks to 3 mo, then MRI and/or validated biomarker before biopsy.
70-74 individualized; not recommended ≥75 or if life expectancy <10 yrs.
Still requires informed consent on benefits, limits, and harms, and departs from USPSTF’s grade C for 55-69.
ACS has moved from ‘discuss it’ to ‘do it’ for average-risk men 50-69 and high-risk men from 45, its biggest change since 2010.”
Title: American Cancer Society guideline for the early detection of prostate cancer, 2026
Authors: Richard M. Hoffman, Andrew M. D. Wolf, Ruth D. Etzioni, Kevin C. Oeffinger, Sana Raoof, Louise C. Walter, Charnita Zeigler-Johnson, Timothy R. Church, Christopher K. Jones, Artie L. Shelton, Elena B. Elkin, Carmen E. Guerra, Rebecca B. Perkins, Ya-Chen Tina Shih, Steven J. Skates, Roman Gulati, Hormuzd A. Katki, Tyler B. Kratzer, Deana Manassaram-Baptiste, William L. Dahut, Robert A. Smith
You can also read:
- Shahrokh Shariat: American Cancer Society Advances Risk-Adapted Prostate Cancer Screening
- Sumanta Pal: A New Guidance From ACS Around Prostate Cancer
- New Prostate Cancer Screening Guidelines Recommend Regular PSA Testing
