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Jasmin Hundal: The impact of breast cancer treatments on fertility in young women
Feb 11, 2025, 08:41

Jasmin Hundal: The impact of breast cancer treatments on fertility in young women

Jasmin Hundal, Hematology Oncology Fellow at Cleveland Clinic, shared her recent article on LinkedIn:

“I am excited to share my latest review paper on the impact of breast cancer treatments on fertility in young women.

Here, Dr. Moore and I review and explore the effects of chemotherapy, hormonal therapies, and targeted agents like PARP inhibitors and CDK4/6 inhibitors on ovarian function and highlight strategies for fertility preservation.

Key Takeaways:

  • Breast cancer treatments can significantly impact ovarian reserve and fertility.
  • As treatment durations extend, some patients may consider interrupting therapy to attempt pregnancy—studies like the POSITIVE trial provide new insights into pregnancy safety after breast cancer.
  • Personalized fertility preservation strategies are crucial to improving young survivors’ quality of life.
  • More research is needed to refine fertility preservation approaches and help patients make informed decisions.

This is a critical topic as more young women are diagnosed with breast cancer and must navigate the balance between treatment and fertility goals. Integrating fertility discussions into oncology care is essential to ensuring comprehensive survivorship planning.”

Impact of Breast Cancer Systemic Therapies on Fertility.

Authors: Jasmin Hundal, et al.
Jasmin Hundal: The impact of breast cancer treatments on fertility in young women