Jan 30, 2025, 08:44
Final analysis of the PRECIOUS phase 3 trial
Paolo Tarantino, Clinical Fellow at Dana-Farber Cancer Institute and Harvard Medical School, shared an article by Yutaka Yamamoto, et al. on X:
“Final analysis of the PRECIOUS phase 3 trial out in Journal of Clinical Oncology.
Despite yielding only a small PFS advantage, pertuzumab rechallenge in HER2+ MBC led to a relevant OS benefit (Δ 10 mo). Could become actionable if T-DXd/pertuzumab make it to the first line.”
Pertuzumab Retreatment for Human Epidermal Growth Factor Receptor 2–Positive Locally Advanced/Metastatic Breast Cancer (PRECIOUS Study): Final Overall Survival Analysis.
Authors: Yutaka Yamamoto, et al.
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