Jarushka Naidoo: Phase II TROPICS-03 trial: Sacituzumab Govitecan (TROP2 ADC) in 2L SCLC
Jarushka Naidoo, Thoracic Oncologist at the Beaumont Hospital Dublin (Ireland), shared a recent article by Afshin Dowlati on X:
“Phase II TROPICS-03 trial: Sacituzumab Govitecan (TROP2 ADC) in 2L Small Cell Lung Cancer in JTO & JTO CRR.
- 43 patients.
- ORR 41.9% (35% plt-resistant, 48% plt-sensitive).
- mPFS 4.4m, mOS 13.60.
- 74.4% g3+ TRAEs.
Some activity here, but treatment not insignificant.”
Authors: Afshin Dowlati, Anne C. Chiang, Andrés Cervantes, Sunil Babu, Erika Hamilton, Shu Fen Wong, Andrea Tazbirkova, Ivana Gabriela Sullivan, Cédric van Marcke, Antoine Italiano, Jilpa Patel, Sabeen Mekan, Tia Wu and Saiama N. Waqar
Dr. Jarushka Naidoo is a thoracic oncologist at the Beaumont Hospital Dublin (Ireland), Professor in RCSI and Adjunct Professor of Oncology at Johns Hopkins University. She currently serves as national lung cancer lead for Cancer Trials Ireland. She serves on several international guideline panels including ASCO and SITC (Society of Immunotherapy for Cancer), and is an experienced clinical trialist- having developed and completed several investigator-initiated, industry-funded and cooperative group clinical trials.
She has received a number of grants including a young investigator award from the International Association for the Study of Lung Cancer (IASLC), Lung Cancer Foundation of America (LCFA), and a career development award from the National Institutes of Health (NIH) KL2-program. She is the IASLC Communications Committee Chair.
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