Yuji Uehara: Are 1976 Palpation Rules Still Best for 21st-Century Medicine?
Aug 30, 2025, 19:23

Yuji Uehara: Are 1976 Palpation Rules Still Best for 21st-Century Medicine?

Yuji Uehara, Medical Oncologist at the National Cancer Center of Japan, shared a post on X about a paper by Illaa Smesseim et al. published in Cancer:

“The origin of the RECIST criteria might surprise you. It all started in 1976, ‘balls under mattresses’. A 50% reduction in size was called a ‘response.’ By-touch rules were then adapted for modern imaging from a 2D area to a simple 1D line (the longest diameter).

So, are rules born from a 1976 palpation experiment still the best for 21st-century medicine?”

Title: The legend of the response evaluation criteria in solid tumors: A historical overview

Authors: Illaa Smesseim, Kevin B. W. Groot Lipman, Ferry Lalezari, Jacobus A. Burgers, Stefano Trebeschi

You can read the Full Article on Cancer.

Yuji Uehara: Are 1976 Palpation Rules Still Best for 21st-Century Medicine?

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