
Tatiana Prowell on the Regulatory Perspectives on CNS Disease in Clinical Trials
Jarushka Naidoo, Full Professor and Consultant Medical Oncologist at Royal College of Surgeons in Irelan, shared a post on X:
“Superb talk by Tatiana Prowell on the Regulatory Perspectives on including patients with CNS disease in clinical trials.
Insights on:
– articulating the case to sponsors
– de-risking trials
– alectinib in ALK+ NSCLC as test case.”
Amir Safavi, Head and Neck Radiation Oncologist of the Department of Radiation Oncology at the University of Toronto, shared this post, adding:
“From Radiation Oncology perspective, crucial that future trials document RT treatment history well (both at baseline & off protocol use) to make sure added CNS efficacy of drugs well understood (see NEJM LTE by Sahgal Arjun et al re: Adagrasib)”
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