How TAF1 Molecule Regulates Hematopoiesis – Sylvester Comprehensive Cancer Center
Sylvester Comprehensive Cancer Center shared a post on LinkedIn about a recent article by Fan Liu et al, adding:
“Science meets leadership.
As director of Sylvester, Dr. Stephen Nimer leads a powerful network of researchers, physicians and patients while continuing his own work in the lab.
‘There’s a lot of creativity in building the cancer center,’ said Dr. Nimer. ‘But as a physician-scientist, I also love the lab.’
In his latest study, Dr. Nimer and colleagues uncovered how a key molecule, TAF1, regulates hematopoiesis, the process by which the body makes new blood cells. When this process breaks down, it can lead to blood cancers. Their discovery opens the door to potential new therapies targeting TAF1.
The new findings ‘not only challenge prevailing models of hematopoietic regulation but also lay the groundwork for innovative clinical applications,’ said Sylvester researcher Dr. Ramin Shiekhattar.
The findings were published July 16 in Developmental Cell.
Title: TAF1 is required for fetal but not adult hematopoiesis in mice
Authors: Fan Liu, Jingyin Yue, Francesco Tamiro, Jun Sun, Pradeep Kumar Reddy Cingaram, Krystal Lisa Hossack, Concepcion Martinez Caja, Ye Xu, Chuan Chen, Felipe Beckedorff, Ramin Shiekhattar, Stephen D. Nimer
Read the Full Article on Developmental Cell
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