Laura Bukavina/X
Aug 9, 2025, 18:57
Laura Bukavina: The Influence of Bladder Microbiome on Intravesical Chemotherapy Response in Bladder Cancer
Laura Bukavina, Urologic Oncologist at Cleveland Clinic, shared a post on X:
“New pub alert. The bladder microbiome may influence intravesical chemotherapy response in bladder cancer. We tested uropathogenic E. coli (UPEC) and gemcitabine
Results>
- Ecoli can enter tumor cells (of course)
- Inactivate gemcitabine → converting it to an inactive metabolite (dFdU)
- Reduce chemo’s ability to kill cancer cells.”
Title: Bladder cancer microbiome and its association with chemoresponse
Authors: Rashida Ginwala, Laura Bukavina, Mohit Sindhani, Erika Nachman, Suraj Peri, Jodie Franklin, John Drevik, Sarah Christianson, Daniel M. Geynisman, Alexander Kutikov, Philip H. Abbosh
Read the Full Article.
More posts featuring L. Bukavina.
-
Challenging the Status Quo in Colorectal Cancer 2024
December 6-8, 2024
-
ESMO 2024 Congress
September 13-17, 2024
-
ASCO Annual Meeting
May 30 - June 4, 2024
-
Yvonne Award 2024
May 31, 2024
-
OncoThon 2024, Online
Feb. 15, 2024
-
Global Summit on War & Cancer 2023, Online
Dec. 14-16, 2023
Aug 9, 2025, 18:55
Aug 9, 2025, 17:52
Aug 9, 2025, 17:47