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Aleix Prat: Patient-Level Meta-Analysis of HER2DX in Early-Stage HER2-Positive Breast Cancer
Jul 15, 2025, 22:45

Aleix Prat: Patient-Level Meta-Analysis of HER2DX in Early-Stage HER2-Positive Breast Cancer

Aleix Prat, Director of Cancer Institute and Blood Disorders at the Hospital Clinic of Barcelona, shared a post on LinkedIn:

“Our new article published in The Lancet Oncology

Very proud to share our latest work on the HER2DX genomic test in early-stage HER2-positive breast cancer.

In this individual patient-level meta-analysis (n = 2,518 patients across 11 studies), HER2DX provides clinically meaningful prognostic stratification, beyond standard clinical–pathological variables and pCR. These results reinforce its value as a clinical tool in precision oncology.

Huge thanks to Dr. Guillermo Villacampa, first author, for his outstanding work, dedication, and leadership throughout this project. And to Dr. Sara Tolaney, senior author, for her continuous support and brilliant scientific guidance.

Thanks also to all co-authors and research teams involved in this collaborative effort. And to REVEAL GENOMICS for supporting this project.

Press Release.”

Title: HER2DX and survival outcomes in early-stage HER2-positive breast cancer: an individual patient-level meta-analysis

Authors: Guillermo Villacampa, Tomás Pascual, Paolo Tarantino, Javier Cortés, José Perez-García, Antonio Llombart-Cussac, Prof Pierfranco Conte, Mario Mancino, Valentina Guarneri, Maria Vittoria Dieci, Adrienne G Waks, Francesco Schettini, Fara Brasó-Maristany, Gaia Griguolo, Beatriz Alonso de Castro, Cristina Reboredo, Silvia Antolín, Coralia Bueno-Muiño, Isabel Echavarría, Sara López-Tarruella, Sara M Tolaney

Read the Full Article.

Aleix Prat

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