10 Papers Suggested Today By Wafik S. El-Deiry

Wafik S. El-Deiry shared a few must-reads papers on X:

1. Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/2

Authors: Markus Vogt, Nevenka Dudvarski Stankovic, Yiliam Cruz Garcia,  Julia Hofstetter, Katharina Schneider, Filiz Kuybu, Theresa Hauck, Bikash Adhikari, Anton Hamann, Yamila Rocca, et al.

2. Mediterranean Diet Is Associated With Lower All-Cause and Cardiovascular Mortality Among Long-Term Cancer Survivors

Authors: Marialaura Bonaccio, Augusto Di Castelnuovo, Simona Costanzo, Emilia Ruggiero, Simona Esposito, Teresa Panzera, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello

3. TWEAK/Fn14 signalling driven super-enhancer reprogramming promotes pro-metastatic metabolic rewiring in triple-negative breast cancer

Authors: Nicholas Sim,  Jean-Michel Carter, Kamalakshi Deka, Benita Kiat Tee Tan, Yirong Sim, Suet-Mien Tan and Yinghui Li

4. Cancer stem cells: advances in knowledge and implications for cancer therapy

Authors: Xianjing Chu, Wentao Tian, Jiaoyang Ning, Gang Xiao, Yunqi Zhou, Ziqi Wang, Zhuofan Zhai, Guilong Tanzhu, Jie Yang and Rongrong Zhou

5. NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance 

Authors: Hengxing Chen, Yun Li, Huafu Li, Xiancong Chen, Huafeng Fu, Deli Mao, Wei Chen, Linxiang Lan, Chunming Wang, Kaishun Hu, Jia Li, Chengming Zhu, Ian Evans, Eddie Cheung, Daning Lu,Yulong He, Axel Behrens, Dong Yin and Changhua Zhang

6. Emerging advances in defining the molecular and therapeutic landscape of small-cell lung cancer

Authors: Triparna Sen, Nobuyuki Takahashi, Subhamoy Chakraborty, Naoko Takebe, Amin H. Nassar, Nagla A. Karim, Sonam Puri and Abdul Rafeh Naqash

7. Engineered matrices reveal stiffness-mediated chemoresistance in patient-derived pancreatic cancer organoids

Authors: Bauer L. LeSavage, Daiyao Zhang, Carla Huerta-López, Aidan E. Gilchrist, Brad A. Krajina, Kasper Karlsson, Amber R. Smith, Kremena Karagyozova, Katarina C. Klett, Michelle S. Huang, Christopher Long, Gernot Kaber, Christopher M. Madl, Paul L. Bollyky, Christina Curtis, Calvin J. Kuo and Sarah C. Heilshorn

8. Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping

Authors: Herman Netskar, Aline Pfefferle, Jodie P. Goodridge, Ebba Sohlberg, Olli Dufva, Sarah A. Teichmann, Demi Brownlie, Jakob Michaëlsson, Nicole Marquardt, Trevor Clancy, Amir Horowitz and
Karl-Johan Malmberg

9. Discriminating Interpatient Variabilities of RAS Gene Variants for Precision Detection of Thyroid Cancer

Authors: Guodong Fu, Ronald S. Chazen, Christina MacMillan, Ian J. Witterick

10. In Vivo Stimulation of Therapeutic Antigen-Specific T Cells in an Artificial Lymph Node Matrix

Authors: Natalie K. Livingston, John W. Hickey, Hajin Sim, Sebastian F. Salathe, Joseph Choy, Jiayuan Kong, Aliyah B. Silver, Jessica L. Stelzel, Mary O. Omotoso, Shuyi Li, et al.

Follow Wafik El-Deiry on X for more such content.

Wafik El-Deiry, MD, PhD, FACP, FRSM, is the Associate Dean for Oncologic Sciences at the Warren Alpert Medical School and Director of the Legorreta Cancer Center at Brown University and Director of the Joint Program in Cancer Biology at Brown University and affiliated hospitals.

Dr. El-Deiry discovered p21(WAF1) as a p53 target gene, cell cycle inhibitor, and tumor suppressor that explained the mammalian cell stress response. Dr. El-Deiry’s research is focused on mechanisms of therapy resistance with major efforts in drug discovery and development.