April, 2024
April 2024
M T W T F S S
1234567
891011121314
15161718192021
22232425262728
2930  
Erman Akkus: Does primary tumor resection prolong OS in inoperable synchronous metastatic CRC?
Mar 3, 2024, 01:59

Erman Akkus: Does primary tumor resection prolong OS in inoperable synchronous metastatic CRC?

Erman Akkus, Medical Oncology Fellow at Ankara University, shared on X:

“Does primary tumor resection (PTR) prolong (OS) in inoperable synchronous metastatic CRC? SYNCHRONOUS and CCRe-IV trials Journal of Clinical Oncology.

Negative study

  • Patients with tumor-related symptoms or diagnostic findings requiring primary surgery (eg, lower GI bleeding requiring transfusion, bowel obstruction, tumor perforation, or intractable pain) excluded.
  • PTR vs no PTR, OS: 16.7 months (95% CI, 13.2 to 19.2) vs 18.6 months (16.2 to 22.3) (P = .191).
  • Serious adverse events more common in No PTR (10.2% vs 18.0%; P = .027)”

Read further.
Source: Erman Akkus/X