Jarushka Naidoo: KN867 trial shows no EFS benefit for SBRT+Pembro in NSCLC
Jarushka Naidoo, Thoracic Oncologist at the Beaumont Hospital Dublin (Ireland), posted the following on X:
“ESMO Immuno 24 Proffered paper
Ph III KN867 trial SBRT+Pembro for stage I/II NSCLC:
- 1:1 SBRT<2wks + pembro x1 yr v pbo
- 448pts
- stopped early for futility
- no EFS benefit, HR, 0.92, P=0.29
- g3+ TRAE 20.4% v 3.7%, 5 deaths v 0
Bad day for RT+IO.”
Dr. Jarushka Naidoo is a thoracic oncologist at the Beaumont Hospital Dublin (Ireland), Professor in RCSI and Adjunct Professor of Oncology at Johns Hopkins University. She currently serves as national lung cancer lead for Cancer Trials Ireland. She serves on several international guideline panels including ASCO and SITC (Society of Immunotherapy for Cancer), and is an experienced clinical trialist- having developed and completed several investigator-initiated, industry-funded and cooperative group clinical trials.
She has received a number of grants including a young investigator award from the International Association for the Study of Lung Cancer (IASLC), Lung Cancer Foundation of America (LCFA), and a career development award from the National Institutes of Health (NIH) KL2-program. She is the IASLC Communications Committee Chair.
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