Myriam Chalabi: Management of Locally Advanced Rectal Cancer: – ASCO Guideline

Myriam Chalabi shared on X:

“Now online in the Journal of Clinical Oncology! Management of Locally Advanced Rectal Cancer: ASCO Guideline. Thankful for the opportunity to contribute – Sepideh Gholami, Van Morris and Manju George!”

Authors: Aaron J. Scott, Erin B. Kennedy, Jordan Berlin, Gina Brown, Myriam Chalabi, May T. Cho, Mike Cusnir, Jennifer Dorth, Manju George, Lisa A. Kachnic, Hagen F. Kennecke, Jonathan M. Loree, Van K. Morris, Rodrigo Oliva Perez, J. Joshua Smith, Matthew R. Strickland, Sepideh Gholami

Management of Locally Advanced Rectal Cancer: ASCO Guideline

Nina Niu Sanford replied to the release of this paper:

“Great reference! Though sad to me that in 2024 our only 2 standard RT regimens are still just long with short course with large fields – regimens created decades ago before any appreciation of molecular differences, non-op, MRI-staging, etc.

So much room to individualize RT in rectal cancer.”

Ane Appelt, Associate Professor at the University of Leeds, also replied:

“Very much agree – we’ve got so much work to do in rectal cancer radonc: adjusting fields and target volumes to stage, optimising dose and fractionation to intent and systemic treatment (rather than just use what worked in the pre-op, no TNT setting), finding the right OARs, etc.”

Myriam Chalabi is a Gastrointestinal Oncologist and clinician scientist at the Netherlands Cancer Institute in Amsterdam. In 2022 she was named one of the 11 early career researchers to watch by Nature Medicine. In 2023 she was awarded the ESMO José Baselga Fellowship for Clinician Scientists.

Nina Niu Sanford is an Assistant Professor and Chief of Gastrointestinal Radiation Oncology at Harvard/Brigham and Women’s Hospital/Massachusetts General Hospital. She specializes in treating gastrointestinal cancers and actively participates in clinical trials combining high-dose radiation therapy with immunotherapy.