May 28, 2025, 23:14

NIH: Technologies for Differential Diagnosis of Symptomatic Conditions

This funding opportunity supports the development of technologies that improve the differential diagnosis of conditions presenting with similar clinical symptoms, particularly those with high diagnostic uncertainty. The goal is to reduce diagnostic delays and errors by creating innovative, affordable, and accessible tools that can be used in diverse healthcare settings, especially where time, expertise, or resources are limited.

Eligibility Criteria:

Higher education institutions (public and private)
For-profit organizations, including small businesses
Nonprofits with or without 501(c)(3) status
Government entities (local, state, tribal, federal)
Foreign institutions and international organizations
Any qualified individual may apply as PD/PI
Multiple applications allowed if they are scientifically distinct
No cost sharing required

Funding Details:

Funding Mechanism: Cooperative Agreement
Activity Code: R61/R33 Phased Innovation Award
Direct Costs:
- R61 phase: Up to $350,000/year for up to 2 years
- R33 phase: Up to $1,000,000/year for up to 3 years
Total Project Period: Up to 5 years
Anticipated Awards: 6–10
Earliest Start Date: April 2026
Clinical trials are optional under this FOA

Deadline:

Letter of Intent Due: October 13, 2025
Application Due: November 13, 2025
Expiration Date: November 14, 2025
Review Date: February/March 2026
Council Date: May 2026

Where to Go for Further Information:

FOA Number: RFA-EB-25-003
Full FOA: grants.nih.gov
Scientific Contact: Grace Peng, Ph.D., NIBIB – [email protected]
Grants Management Contact: Cindy Fultz, NIBIB – [email protected]
Apply via Grants.gov or NIH ASSIST

cancer Cancer diagnostics clinical trial optional Diagnostic tools differential diagnosis early detection healthcare equity Healthcare Innovation low-resource settings Medical Technology NIBIB NIH OncoDaily Oncology R61 R33 grant

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