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Sami (Papacek) Mansfield: The discussion of myokines in cancer is exciting
Feb 26, 2025, 13:04

Sami (Papacek) Mansfield: The discussion of myokines in cancer is exciting

Sami (Papacek) Mansfield, Founder of Cancer Wellness for Life, shared a post by Jackson Fyfe, Lecturer at Deakin University, on LinkedIn, adding:

“The discussion of myokines in cancer is particularly exciting!

How exercise can produce these little ‘bad-a**’ molecules that can “talk back” to cancer cells is incredible!

The simple fact that exercise has so many benefits to individuals with cancer, I am continually perplexed why this isn’t a standard conversation from every area of clinical delivery but I remind myself that most people simply are unaware so I am incredibly grateful for the elevation of this topic from experts such as Jackson Fyfe.”

Quoting Jackson Fyfe‘s post:

“Exercise has powerful neuroprotective effects.

But does intensity matter?

Muscle contractions release myokines – chemical messengers that boost BDNF, a key driver of neuroplasticity, learning, memory, and brain resilience.

Emerging evidence suggests high-intensity exercise may elevate neuroprotective myokine levels as much as, or more than, moderate-intensity workouts.

Why movement is essential for long-term brain health.

Awesome review from James Broatch, David J Bishop, Prof Itamar levinger and team:

Zare N, Bishop DJ, Levinger I, Febbraio MA, Broatch JR. Exercise intensity matters: A review on evaluating the effects of aerobic exercise intensity on muscle-derived neuroprotective myokines. Alzheimers Dement. 2025 Feb 19;11(1):e70056.”

Sami (Papacek) Mansfield