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Novel mechanisms of resistance in Chronic lymphocytic leukemia – Blood Journal
Mar 24, 2025, 13:50

Novel mechanisms of resistance in Chronic lymphocytic leukemia – Blood Journal

Blood Journal shared a paper Constantine S. Tam and colleagues authored on X:

“Bruton tyrosine kinase inhibitors are an established standard of care in chronic lymphocytic leukemia.”

Novel mechanisms of resistance in Chronic lymphocytic leukemia - Blood Journal

Justin Taylor, Assistant Professor at the UM Sylvester Comprehensive Cancer Center, shared this post, adding:

“Great review Blood Journal!

Our study on BTK mutations kinase impaired and kinase proficient responding to degraders with Nurix Therapeutics and MSKCC is in the STAT Madness 2025 competition! Read more and vote here.”

Novel mechanisms of resistance in CLL: variant BTK mutations in second-generation and noncovalent BTK inhibitors

Authors: Constantine S. Tam, Shalini Balendran, Piers Blombery

 Chronic lymphocytic leukemia