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A classical epithelial cancer cell state drives resistance to KRAS inhibition in Pancreatic Cancer – NCI Division of Cancer Biology
Anupriya Singhal/mskcc.org
Dec 25, 2024, 18:18

A classical epithelial cancer cell state drives resistance to KRAS inhibition in Pancreatic Cancer – NCI Division of Cancer Biology

NCI Division of Cancer Biology shared a post on X:

“Using reporter systems and preclinical models in a study funded by an NCI MERIT Award, Tuomas Tammela, MSKCC et al. found that a classical epithelial cancer cell state drives resistance to KRAS inhibition in Pancreatic Cancer.”

A classical Epithelial State Drives Acute Resistance to KRAS Inhibition in Pancreatic Cancer

Authors: Anupriya Singhal et al.

epithelial cancer cell

AACR Cancer Discovery Anupriya Singhal cancer Cancer Discovery Doron Betel Elisa de Stanchina Hannah C. Styers Huijin Feng Hulya Sahin Ozkan Iok In Christine Chio James G. Christensen Jill Hallin Jonathan Rub Jung Yun Kim Olca Basturk Olivera Grbovic-Huezo OncoDaily Oncology Pancreatic Cancer Rona Yaeger Stefan R. Torborg Tuomas Tammela Tuomas TammelaSinghal Yan Yan Zeynep Cagla. Tarcan Zhuxuan Li
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