Estela Rodriguez: Fascinating report on utility of cfDNA for detecting occult cancers by Amy E. Turriff et al.
Estela Rodriguez, Associate Director of Community Outreach, posted on X about recent paper by Amy E. Turriff et al., titled “Prenatal cfDNA Sequencing and Incidental Detection of Maternal Cancer” published on The New England Journal of Medicine.
Authors: Amy E. Turriff, Christina M. Annunziata, Ashkan A. Malayeri, Bernadette Redd, Miroslava Pavelova, Ian S. Goldlust, Padma Sheila Rajagopal, Jielu Lin, and Diana W. Bianchi.
“Fascinating report on utility of cfDNA (liquid biopsies) and whole body MRI for detecting occult cancers Prenatal cfDNA Sequencing and Incidental Detection of Maternal Cancer | New England Journal of Medicine.
- In this cohort: 52/107 (49%) of women w abnormal cfDNA had an occult cancer
- Most cancers detected heme malignancies (31), solid tumors (20)
- MRI sensitivity (98%), specificity (89%).”
Estela (Estelamari) Rodriguez is Associate Director of Community Outreach and Co-Lead of Thoracic Site Disease Group of the Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine. She is board certified in medical oncology and hematology. She has a special interest in the early detection of lung cancer and increasing access to clinical trials.
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