Yüksel Ürün: PEACE-3 Reveals Sequencing Strategies Are Key in mCRPC
Yüksel Ürün/X

Yüksel Ürün: PEACE-3 Reveals Sequencing Strategies Are Key in mCRPC

Yüksel Ürün, Medical Oncology Professor at Ankara University School of Medicine, shared a post on X:

EORTC 1333 / PEACE-3 final OS.

Enzalutamide + Radium-223 improved OS

HR 0.76. rPFS also better. Toxicity higher but manageable. Bone protection mandatory.

But here is the real question: Most mCRPC patients already received an ARPI earlier.

So where does this fit today? Likely in a selected group:

  • Bone-only disease.
  • Good performance status.
  • Limited prior ARPI exposure or long ARPI response.
  • No visceral metastases.

Sequencing now matters more than ever.

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