Yago Garitaonaindia, Translational Research Fellow at CCIT-DK – National Center for Cancer Immune Therapy of Denmark, shared a post on LinkedIn about a recent article by Sanjeev Kulgod et al, published in Journal of Clinical Oncology:
“Dogs chasing cancer, not postmen
A phase II study in JCO used detection dogs plus Bayesian modeling to screen for multiple cancers from breath. 3,275 participants. AUC 0.962. Sensitivity and specificity >90% across 7 cancer types and all stages.
The dogs are the fun part.
The real question is: how do you triage cancer at scale with almost no resources?
In India, ~80% of cancers are diagnosed at stage III-IV. Screening coverage: 1%. You don’t need a perfect test to you need cheap, noninvasive, and sensitive enough to cover a huge population.
Maybe the volatilome deserves more attention than we’ve given it?
Kulgod et al., JCO 2026 | Disclaimer; Not my primary field — curious what those in global oncology or early detection think.”
Title: Canine Olfaction Combined With Bayesian Modeling for Multicancer Detection From Breath Samples: A Phase II Study in India
Authors: Sanjeev Kulgod, Basavaraj Patil, Shashidhar Kallappa, Rakesh Ramesh, Kiran Kulkarni, Somashekhar SP, Swaratika Majumdar, Akshita Singh, Claire Guest, Rob Harris, Ido Aviram, Sahana Shanbhag, Achin Parashar, Sree Subha Ramaswamy, Itamar Bitan, Akash Kulgod
Read the Full Article on Journal of Clinical Oncology

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