Vivek Subbiah, Chief of Early-Phase Drug Development at the Sarah Cannon Research Institute, shared some papers on X:
1. Title: Investigation of Profile-Related Evidence Determining Individualized Cancer Therapy (I-PREDICT) N-of-1 Precision Oncology Study: Molecular Profiling to Match Individually Dosed, Personalized Drug Combinations
Authors: Jason K. Sicklick, Daisuke Nishizaki, Hirotaka Miyashita, Ryosuke Okamura, Michael E. Hahn, Mina Nikanjam, Paul T. Fanta, David E. Piccioni, Hitendra Patel, Ramez N. Eskander, Rana R. McKay, Jeffrey S. Ross, J. Jack Lee, Scott M. Lippman, Shumei Kato, and Razelle Kurzrock.
You can read the Full Article in the Journal of Clinical Oncology.

2. Title: Fasting boosts breast cancer therapy efficacy via glucocorticoid activation
Authors: Nuno Padrão, Tesa M. Severson, Sebastian Gregoricchio, Ana Guijarro, Catrin Lutz, Daniel Taranto, Stefan Hutten, Francesca Ligorio, Angelica Persia, Merel Roest, Joyce Sanders, Ji-Ying Song, Sara Pires-Oliveira, Maria Donaldson Collier, Hugo Horlings, Livia Pisciotta, Filippo de Braud, Claudio Vernieri, Leila Akkari, Jos Jonkers, Alessio Nencioni, Irene Caffa, Wilbert Zwart
You can read the Full Article in Nature.

3. Title: Intratumoural vaccination via checkpoint degradation-coupled antigen presentation
Authors: Yu Han, Yicong Ma, Miao Pei, Shenyi Yin, Jiahao Wang, Liyu Guo, Yike Fang, Weiming Guo, Chunjiang Deng, Su Zhao, Xueyin Lu, Jianzhong Jeff Xi, Heng Zhang, Peng R. Chen
You can read the Full Article in Nature.

4. Title: Going beyond genomics in precision oncology
Authors: Irene Paassen, Mark A. Rubin
You can read the Full Article in Nature Medicine.

5. Title: Trastuzumab Deruxtecan Resistance via Loss of HER2 Expression and Binding
Authors: Wanyi Chen, Avantika Gupta, Nicholas Mai, Sharanya Nag, Joshua S. Lau, Sukrit Singh, John D. Chodera, Bo Liu, Elisa de Stanchina, Fresia Pareja, Atif Ali Hashmi, Miriam M. Lieberman, Shanu Modi, Jacqueline Bromberg, Pedram Razavi, Joshua Z. Drago, and Sarat Chandarlapaty.
You can read the Full Article in Cancer Discovery.

6. Title: Sodium-Glucose Cotransporter 2 Inhibitors for Patients With Prostate Cancer Undergoing Hormone Therapy
Authors: Ruofan Shi, Yongle Zhan, Ruochen Ma, Salida Ali, Chi Yao, Tsun Tsun Stacia Chun, Ada Tsui-Lin Ng, Matthew Kin-Liang Chiu, Bryan Cho Wing Li, and Rong Na.
You can read the Full Article in JAMA Oncology.

7. Title: Clonal Hematopoiesis and Cardiovascular Disease Risk After Cancer Therapy in Patients With Solid Tumors
Authors: Derek Shyr, Yash Pershad, Kun Zhao, Ashwin Kishtagari, Robert W. Corty, Eric Shinohara, Ben Ho Park, J. Brett Heimlich, Leo Luo, and Alexander G. Bick.
You can read the Full Article in JAMA Oncology.

8. Title: Immune Checkpoint Inhibitor–Associated Cardiovascular Toxic Effects: International Cardio-Oncology Society Position Statement
Authors: Joerg Herrmann, Ana Barac, Joseph Carver, Richard K. Cheng, Andres Daniele, Susan Dent, Elena Deych, Dae Hyun Lee, Daniel Lenihan, Darryl P. Leong, Jennifer Liu, Teresa Lopez-Fernandez, Alexander R. Lyon, Michael Fradley, Ariane V. S. Macedo, Meghan J. Mooradian, Anju Nohria, Charles Porter, Tienush Rassaf, Giselle Suero-Abreu, Aaron L. Sverdlov, Paaladinesh Thavendiranathan, Tomas G. Neilan, and Joshua D. Mitchell.
You can read the Full Article in JAMA Oncology.

9. Title: Ocular Toxic Effects During Mirvetuximab Soravtansine Therapy
Authors: Ali J. Haidar, Angela Chen, Judy L. Chen, Saba Al-Hashimi, Reza S. Ghaffari, Simon Fung, Jordyn Silverstein, Gottfried E. Konecny, and Edmund Tsui.
You can read the Full Article in JAMA Oncology.

10. Title: Toripalimab vs Dacarbazine as First-Line Therapy for Advanced Melanoma of Acral Subtype: The Phase 3 MELATORCH Randomized Clinical Trial
Authors: Xinan Sheng, Gang Huang, Meiyu Fang, Ke Li, Di Wu, Xiaoshi Zhang, Jing Chen, Dongyuan Zhu, Yu Chen, Hongxia Li, Quanli Gao, Lin Wu, Bixia Tang, Xieqiao Yan, Ruichao Zeng, Junliang Li, Wenbo Yu, Jing Xu, Yu Hao, Chunlei Jin, Jianjun Zou, and Jun Guo.
You can read the Full Article in JAMA Oncology.

More posts featuring Vivek Subbiah.