The Immunobuddies Podcast: A Wi-Fi Password From the 90’s… or an Actual Toxicity?
The Immunobuddies Podcast/X

The Immunobuddies Podcast: A Wi-Fi Password From the 90’s… or an Actual Toxicity?

The Immunobuddies Podcast shared a post on X:

Episode 181 is live!

RS3PE – A Wi-Fi password from the 90’s… or an actual toxicity?

Before you try typing it into your old PC, RS3PE is actually Remitting Seronegative Symmetrical Synovitis with Pitting Edema – a rare inflammatory rheumatological condition causing sudden symmetrical joint inflammation and puffy, pitting hands/feet, and yes… it can show up as an immune-related toxicity.

In this episode, we unpack:

  • What RS3PE really is
  • Why it’s being seen with immunotherapy
  • How to recognise it (and not just blame bad Wi-Fi)

Listen now and find out why this “password” definitely shouldn’t be ignored.”

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The Immunobuddies Podcast

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Medically reviewed Feb 17, 2026 by Armen Gevorgyan, MD