Tejas Patil, Assistant Professor of Thoracic Oncology; Vice Head of Clinical Affairs, Division of Oncology, University of Colorado Anschutz, shared a post on X:
“Catching up after a Busy April and wanted to sincerely thank co-chairs Drs. Tina Cascone and Stephen V Liu, for an Amazing TLC conference!
In reflecting on our session on HER2, MET, BRAF, and KRAS altered NSCLC, I noticed Two major themes in the panel discussion.”

“THEME 1: What is the optimal sequencing strategy for patients with HER2 mutations? We have 1L zongertinib approval, but should we intensify with HER2 TKI + platinum / pem, HER2 TKI + HER2 ADC, or something else (like a modified BRIGHTSTAR) approach? What about non-TKD HER2? Fantastic review article on HER2 cancers.”

“THEME 2: What is optimal sequencing strategy for pts with MET, BRAF, and KRAS NSCLC? When do you prioritize an IO first strategy vs TKI first strategy, given that a subset of patients with these mutations will have IO responsive disease? Two EXCELLENT articles on this topic!”

“Thanks to my colleagues Luda Bazhenova, Melina Marmarelis, Ferdinandos Skoulidis, Justin Gainor, Ryan Gentzler, Misako Nagasaka for a WONDERFUL panel discussion and the conference organizers Idealogy for Texas Lung26!”
Title: HER2-targeted therapies beyond breast cancer — an update
Authors: Jeesun Yoon, Do-Youn Oh
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Title: Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cancer
Authors: Marcelo V Negrao, Ferdinandos Skoulidis, Meagan Montesion, Katja Schulze, Ilze Bara, Vincent Shen, Hao Xu, Sylvia Hu, Dawen Sui, Yasir Y Elamin, Xiuning Le, Michael E Goldberg, Karthikeyan Murugesan, Chang-Jiun Wu, Jianhua Zhang, David S Barreto, Jacqulyne P Robichaux, Alexandre Reuben, Tina Cascone, Carl M Gay, Kyle G Mitchell, Lingzhi Hong, Waree Rinsurongkawong, Jack A Roth, Stephen G Swisher, Jack Lee, Anne Tsao, Vassiliki Papadimitrakopoulou, Don L Gibbons, Bonnie S Glisson, Gaurav Singal, Vincent A Miller, Brian Alexander, Garrett Frampton, Lee A Albacker, David Shames, Jianjun Zhang, John V Heymach
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Title: Immunomodulatory role of oncogenic alterations in non-small cell lung cancer: a review of implications for immunotherapy
Authors: Maritza Ramos-Ramírez, Enrique Caballe-Pérez, José Lucio-Lozada, Eunice Romero-Nuñez, Cesar Castillo-Ruiz, Lorena Dorantes-Sánchez, Diana Flores-Estrada, Gonzalo Recondo, Pedro Barrios-Bernal, Luis Cabrera-Miranda, Heyman Bravo-Dominguez, Norma Hernández-Pedro, Oscar Arrieta
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Other Articles Featuring Tejas Patil on OncoDaily.