Spencer Knight
Novartis/X

Spencer Knight: Breaking News – Novartis to Acquire Avidity Bio for $12B 

Spencer Knight, Business Development Director – Biotechnology at Hartmann Young, shared a post on LinkedIn:

Breaking News: Novartis to Acquire Avidity Bio for $12B 

Novartis is strengthening its late-stage neuroscience portfolio by acquiring Avidity Biosciences for $72 per share in cash, valuing the RNA and Neuromuscular biotech at approximately $12 billion.

Key Highlights:

  •  Delpacibart zotadirsen (AOC 1044) – Late-stage program for Duchenne muscular dystrophy (DMD)
  •  Delpacibart etedesiran (AOC 1001) – Late-stage program for myotonic dystrophy type 1 (DM1)
  •  Delpacibart braxlosiran (AOC 1020) – Late-stage program for facioscapulohumeral muscular dystrophy (FSHD)

All three candidates are in registrational studies with peak sales projected at $420M, $4.3B, and $3.2B, respectively. Acquisition follows the planned spin-off of Avidity’s early cardiology programs into a new public company, SpinCo.

Great to see diseases such as FSHD, DMD and DM1 being highlighted.

This deal accelerates Novartis’ expansion in rare neuromuscular diseases and strengthens its proprietary RNA-targeting platform. Avidity’s groundbreaking work in antibody oligonucleotide conjugates (AOCs™) now has a global stage.

Congratulations to the teams at Novartis and Avidity Biosciences for driving innovation forward for patients!”

Spencer Knight

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