Voices

Aug 25, 2025, 21:47

Simon Mooijaart: Patient Perspectives on Antithrombotic Therapy in Advanced Cancer

Simon Mooijaart, Chair of Gerontology and Geriatrics at Leiden University Medical Center, shared a post on LinkedIn:

“‘Who am I to stop taking my medication?’ – a patient asked in our recent study.

That question stayed with me.

When we as professionals want to stop medication, we often focus on the clinical reasoning: Risk of bleeding. Limited benefit. A burden.

All true — but not enough.

Patients need more than facts. They need support to engage in that decision. And some simply don’t feel it’s their place.

This is one of the key findings in our new qualitative study, part of the SERENITY consortium:

Some patients are willing and able to co-decide about stopping antithrombotics
Others defer to clinicians, feeling it’s not their role — especially near the end of life
The difference isn’t about education or attitude. It’s about context, trust, timing, framing

Advance care planning isn’t just about what we do — but how we decide it. Together. Stopping medication starts with the patient

Applause to the lead authors for this inspiring work!

How do you approach deprescribing conversations? What helps make it truly shared?

In SERENITY, we’re working on a shared decision-making tool to support cancer patients, families, and clinicians in making informed, evidence-based choices about antithrombotic therapy near the end of life.

Learn more about the consortium here.”

Simon Mooijaart

Title: “Who am I to say that I’m not going to take it”: patient perspectives on decisions about antithrombotic therapy in the context of advanced cancer

Journal: Thrombosis Research

Authors: Elin Baddeley, Carme Font, Isabelle Mahé, Michelle Edwards, Stephanie Sivell, Kate J. Lifford, Victoria Mailen Arfuch, Nuri Coma-Auli, Mette Søgaard, Helle Enggaard, Hélène Helfer, Nassima Si Mohammedi, Kathy Seddon, Mark Pearson, Simone P. Mooijaart, Sebastian Szmit, F.A. Klok, Simon Noble, Anette Arbjerg Højen

Read the full article.

Simon Mooijaart

More posts featuring antithrombotic therapy on OncoDaily.

Anette Arbjerg Højen antithrombotic therapy cancer Carme Font Elin Baddeley F.A. Klok Hélène Helfer Helle Enggaard Isabelle Mahé Kate J. Lifford Kathy Seddon Leiden University Medical Center Mark Pearson Mette Søgaard Michelle Edwards Nassima Si Mohammedi Nuri Coma-Auli OncoDaily Oncology Sebastian Szmit SERENITY Simon Mooijaart Simon Noble Simone P. Mooijaart Stephanie Sivell Victoria Mailen Arfuch

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