Rishabh Jain: Upper GI is Bringing Some of the Biggest Practice-Changing Data to ESMOGI26

Rishabh Jain: Upper GI is Bringing Some of the Biggest Practice-Changing Data to ESMOGI26

Rishabh Jain, Medical Oncologist at AIIMS, shared a post on X:

“Upper GI is bringing some of the biggest practice-changing data to ESMOGI26.

Here are the Top 5 Upper GI Cancer abstracts I’m watching most closely.

1. 493O | STAR-221

Can domvanalimab + zimberelimab + chemotherapy outperform nivolumab + chemotherapy in first-line HER2-negative advanced gastric/GEJ adenocarcinoma?

2. 494O | HERIZON-GEA-01 (HRQoL)

Do the survival gains with zanidatamab + chemotherapy ± tislelizumab also translate into better quality of life for HER2-positive disease?

3. 495RO | HERIZON-GEA-01 (PFS2 Analysis)

Does first-line zanidatamab continue to provide benefit even after subsequent lines of therapy?

4. 496RO | EORTC ASPIRE

Can different PD-L1 assays and scoring systems be used interchangeably in gastroesophageal adenocarcinoma?

5. 344RO | Futibatinib + Zimberelimab + Chemotherapy

An early look at a novel first-line combination for advanced biliary tract cancer that could influence the broader upper GI treatment landscape.

Which upper GI abstract are you looking forward to the most?”

Rishabh Jain

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