Rashid Lui: First-in-Class Oral Selective p53 Reactivator Looks Promising
Rashid Lui/X

Rashid Lui: First-in-Class Oral Selective p53 Reactivator Looks Promising

Rashid Lui, Associate Consultant at Hospital Authority and Honorary Clinical Assistant Professor at CUHK Medicine, shared a post on LinkedIn:

“And this is why, ladies and gentlemen, I have pivoted more and more towards oncology

This latest phase I study in NEJM Group of a first-in-class, Oral selective p53 reactivator looks promising

Cancer biomarkers and pathways that we were forced to study in med school are now potentially druggable!”

Title: Phase 1 Study of Rezatapopt, a p53 Reactivator, in TP53 Y220C–Mutated Tumors

Authors: Ecaterina Dumbrava, Geoffrey Shapiro, Aparna Parikh, Melissa Johnson, Anthony Tolcher, John Thompson, Anthony El-Khoueiry, Andrae Vandross, Shivaani Kummar, Dale Shepard, Kim LeDuke, Lisa Sheehan, Leila Alland, Arshad Haque, Deepika Jalota, Marc Fellous, Alison Schram

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Rashid Lui: First-in-Class Oral Selective p53 Reactivator Looks Promising

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