Purdue Institute for Cancer Research shared a post on LinkedIn:
“Purdue researchers, including Nicolás Morato and R. Graham Cooks, have developed a next-generation platform that integrates chemical synthesis, biological testing, and mass spectrometry into a single automated workflow, accelerating early-stage drug discovery, including the search for new cancer therapies.
Published in PNAS, the work reflects more than a decade of development built on Purdue’s pioneering DESI-MS technology. The project was supported by The National Institutes of Health’s National Center for Advancing Translational Sciences (NCATS) through its ASPIRE program.
Title: Early-stage drug discovery in a new-generation ultrahigh-throughput mass spectrometry platform
Authors: Nicolás M. Morato, Yunfei Feng, Kitmin Chen, Kai-Hung Huang, Alexis Owen, Joseph V. Caruso, Beinan Yang, Samadhi C.Kulathunga, Andrew D. Mesecar, Carleen Klumpp-Thomas, Aco Radujevic, Alexander G. Godfrey, Sean Gardner, Dobrila D. Rudnicki, Matt Galbraith, Adam Gloeckner, Csaba Hajdu, Steven D. Pringle, Michael Morris, Julia Balog, R. Graham Cooks
Read the Full Article on PNAS
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