Paul Northcott, Co-Director, Neurobiology and Brain Tumor Program (NBTP), St. Jude Comprehensive Cancer Center at St. Jude Children’s Research Hospital, shared a post on LinkedIn:
“Hot off the press Nature a game-changing liquid biopsy study where we describe “M-PACT”, a novel AI-based method for classifying brain cancer based on cell-free DNA methylation …this work represents a prime example of effective team science, achieved by bringing together an international team to jointly address a fundamental challenge in the field …big congratulations to Kyle Smith, Tom Fischer, Katie Han, Kristian Pajtler, Kendra Maass, & all members of our incredible study team.”
Title: M-PACT leverages cell-free DNA methylomes to achieve robust classification of pediatric brain tumors
Authors: Kyle S. Smith, Tom T. Fischer, Katie Han, Anna Kostecka, Hong Lin, Daniel Senfter, Taha Soliman, Natalia Stepien, Stefanie Volz, Nathalie Schwarz, Tatjana Wedig, Sibylle Madlener, Christine Haberler, Sandeep K. Dhanda, Santhosh A. Upadhyaya, Patrick R. Blackburn, Maria T. Schmook, Judith de Bont, Hannu Haapasalo, Justina Dargvainiene, Frank Leypoldt, Stefan M. Pfister, Esther Hulleman, Brent A. Orr, Paul A. Northcott
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