Paul Brown: Calling for NCCN Guideline Updates on Low-Dose Whole-Brain Radiotherapy in PCNSL
Paul Brown/mayo.edu

Paul Brown: Calling for NCCN Guideline Updates on Low-Dose Whole-Brain Radiotherapy in PCNSL

Paul Brown, Radiation Oncologist at Mayo Clinic, shared a post on LinkedIn:

“Editorial PCNSL

Low dose WBRT:

  • better cognitive outcomes (due to better CNS control?)
  • 60yo OS benefit
  • Consider LD-WBRT if not good transplant candidate
  • LD-WBRT is a modern consolidative therapy

Contact your NCCN Reps to fix guidelines.

Excellent editorial Gustav Cederquist, Joachim Yahalom, Brandon Imber.

Thanks Jeff Ryckman, for alerting me to NCCN –I have contacted my NCCN reps asking for changes and updates to the PCNSL sections.”

Title: A Little Less Gray: Reduced Dose Whole Brain Radiation Therapy Consolidation in Primary Central Nervous System Lymphoma Proves to Be a Winner in a Key Randomized Study

Authors: Gustav Cederquist, Joachim Yahalom, Brandon Imber

Read the Full Article on International Journal of Radiation Oncology, Biology, Physics

Paul Brown: Calling for NCCN Guideline Updates on Low-Dose Whole-Brain Radiotherapy in PCNSL

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