Pat Soon-Shiong

Pat Soon-Shiong: ALC and NLR – The Questions That Could Change How We Treat Cancer

Pat Soon-Shiong, Chairman of Chan Soon-Shiong Family Foundation, Executive Chairman at ImmunityBio, and Executive Chairman of the Los Angeles Times, shared a post by Camus, adding:

“Ask your doctor: “what is my ALC?”and the reaction may be interesting . Next ask “what is my NLR ratio”? Trying very hard to discuss this important science to evolve our thinking of how to treat our patients with cancer. Publication on lung cancer and 10 tumor types submitted.”

Quoting Camus‘s post:

“Dr. Patrick Soon-Shiong delivers a seismic critique of modern oncology: “For 75 years, we have operated on a fundamental fallacy.” We’ve waged a “war on cancer” with the tools of war – poisons and radiation.

But in nuking the tumor, we nuke the patient’s own first line of defense: their natural killer cells and T-cells. He exposes a vicious, maddening cycle:

  1.  Chemo/radiation induces anemia.
  2.  We administer a drug (Epogen) to counteract it… only to enable more chemo.
  3.  That chemo wipes out neutrophils.
  4.  We administer another drug (Neupogen) to counteract that… only to enable even more chemo.

This is the madness. We are systematically destroying the body’s innate immune system to save it. The core of the problem? Regulatory dogma. The FDA‘s primary metric for drug approval is MTD – Maximum Tolerated Dose.

Find the highest dose of poison a human can endure without dying. And the endpoint? Tumor shrinkage, not overall survival. A tumor can shrink while the patient dies. And that, astoundingly, has been acceptable. Dr. Soon-Shiong challenges the world to recognize this 75-year wrong turn. It is a plea for a paradigm shift from poisoning to empowering, from destruction to restoration.

The future of medicine must look back at this era and ask, ‘Why were we doing that?’

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