Oscar Tahuahua, Medical Oncology Fellow at the National Cancer Institute of Mexico, shared a post on X:
“Up to 40% of lung cancer happens in people we don’t even screen.
Up to 30-40% in East Asia occurs in never smokers.
Risk concentrates on:
- Women OR ~2.0
- Asian ethnicity ~2.3x
- Family history increases up to 3.9x
Biologically distinct:
- EGFR mutations in ~50%
- Increased mitochondrial DNA damage linked to progression and worse survival.
This is not smoking related disease, it is a different biology. ”
Title: Lung Cancer in Never Smokers: Genetics, Epidemiology, Environmental Exposures, and Distinct Immune Landscape
Authors: Jiahua Lu, Elaine Shum, Robert Samstein, Diddier Prada, Fred Hirsch
Other articles featuring Oscar Tahuahua on OncoDaily.