Satheesh Kumar Poolakkad Sankaran: Oral Mucositis Quadruples Infection Risk After HSCT
Satheesh Kumar Poolakkad Sankaran, Director of WE-BRIGHT Network at the University at Buffalo, shared a post on LinkedIn about his recent paper coauthored with colleagues:
“A Battle at the Body’s Frontline
The mouth is the gatekeeper to the body’s defenses. During hematopoietic stem cell transplantation (HSCT), a silent but intense battle takes place, and one of the most formidable enemies is oral mucositis (OM).
Our latest publication in Cancers shows that OM increases the risk of infectious invasions by a factor of four.
In this oral-systemic battle, the challenges include harsh conditioning regimens, the toxicity of methotrexate, vulnerabilities in certain patient populations, and the prolonged period of neutropenia.
Protecting the oral gateway is not only a matter of patient comfort can also be a critical, life-saving intervention in HSCT care.
Read the full study here.”
Title: Elevated Likelihood of Infectious Complications Related to Oral Mucositis After Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-Analysis of Outcomes and Risk Factors
Journal: Cancers
Authors: Susan Eichhorn, Lauryn Rudin, Chidambaram Ramasamy, Ridham Varsani, Parikshit Padhi, Nour Nassour, Kapil Meleveedu, Joel B. Epstein, Benjamin Semegran, Roberto Pili, Poolakkad S. Satheeshkumar
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