Nicole Stout, Senior Director of Survivorship and Wellness at the American Cancer Society, shared a post on LinkedIn by JAMA Oncology, adding:
“This should lead us to the question: if we mitigate fatigue before initiating systemic therapy, do we reduce adverse outcomes? When unmanaged medical conditions exist prior to treatment, and we know they can contribute to adverse outcomes, we must act to manage them!
The good news is that there is an incredibly robust evidence base to support exercise for reducing fatigue!
What can that look like?
- Prehabilitation programs that combine exercise and CBT- evidence-based interventions for cancer related fatigue
- Baseline functional testing to understand what is pretreatment ‘normal’ and leveraging a prospective surveillance approach to understand when clinically meaningful change occurs and intervene!
This is precision medicine!”
Quoting JAMA Oncology’s post:
“Among over 7000 patients with cancer, higher baseline fatigue before systemic therapy was linked to an increased risk of severe, life-threatening, and fatal adverse events.”
Title: Baseline Fatigue and Severe Toxic Effects in Patients With Cancer Receiving Systemic Therapy
Authors: Joseph M. Unger, Michael J. Fisch, Salene M. W. Jones, N. Lynn Henry, and Dawn L. Hershman
You can read the Full Article in JAMA Oncology.

More posts featuring Nicole Stout.